Zelnorm in the USA.

State Department to monitor the quality of medicines and food of China (SFDA) ordered the suspension of production, sale and use of the drug Zelnorm for the treatment of irritable bowel syndrome (IBS). Such a step was taken after a course of studies in China and abroad revealed that drug use is linked to increased risk of heart attack and stroke. According to SFDA, the risk in the application of the drug in some patients exceeds the benefit from it. Zelnorm was approved for use in IBS and konstipatsii in 2002, Since 2003, when the drug appeared in the Chinese market, the National Monitoring Centre for side effects of medicines PRC received 98 applications. According to the center, mainly side effects were diarrhea and nausea, although in one case was recorded tachycardia, in two - heartbeat palpitations and in another - low blood pressure. However, a review of surveillance data for 18 thousand patients conducted by Novartis, showed the number of patients who have developed cardiovascular disease, quite significantly. Some countries, including U.S. and Canada, withdrew the drug from sale. Total Zelnorm approved in 55 countries around the world. In China, the drug companies produced 3.

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